Diógenes S Santos Selected Research

Shikimate dehydrogenase

11/2009	The conserved Lysine69 residue plays a catalytic role in Mycobacterium tuberculosis shikimate dehydrogenase.
4/2006	Functional shikimate dehydrogenase from Mycobacterium tuberculosis H37Rv: purification and characterization.
10/2002	Cloning and expression of functional shikimate dehydrogenase (EC 1.1.1.25) from Mycobacterium tuberculosis H37Rv.

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Diógenes S Santos Research Topics

Disease

28	Tuberculosis (Tuberculoses) 01/2018 - 10/2002
4	Neoplasms (Cancer) 12/2014 - 04/2008
2	Infections 01/2018 - 09/2009
2	Coinfection 01/2011 - 04/2006
1	Diarrhea 12/2014
1	Mucositis 12/2014
1	Edema (Dropsy) 09/2009
1	Parasitic Diseases (Parasitic Disease) 08/2009
1	Extensively Drug-Resistant Tuberculosis 08/2008
1	Neutropenia 04/2008
1	Neglected Diseases 03/2007
1	Rare Diseases (Rare Disease) 03/2007
1	Latent Tuberculosis 03/2007
1	Communicable Diseases (Infectious Diseases) 05/2006
1	Leukemia 10/2005
1	Autoimmune Diseases (Autoimmune Disease) 10/2005
1	Inborn Genetic Diseases (Disease, Hereditary) 10/2005
1	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 02/2005

Drug/Important Bio-Agent (IBA)

12	Pharmaceutical PreparationsIBA 01/2018 - 04/2003
7	EnzymesIBA 09/2013 - 10/2005
4	Isoniazid (Ftivazide)FDA LinkGeneric 01/2018 - 01/2006
4	Anti-Bacterial Agents (Antibiotics)IBA 08/2008 - 04/2003
3	pentacyano(isoniazid)ferrate(II)IBA 01/2018 - 01/2014
3	Shikimate dehydrogenaseIBA 11/2009 - 10/2002
2	KininsIBA 01/2018 - 09/2009
2	Purine-Nucleoside PhosphorylaseIBA 01/2012 - 06/2009
2	purineIBA 01/2012 - 08/2009
2	Antitubercular AgentsIBA 11/2009 - 03/2007
2	shikimateIBA 11/2009 - 08/2008
2	chorismate synthaseIBA 04/2008 - 03/2007
2	Aromatic Amino Acids (Aromatic Amino Acid)IBA 01/2008 - 04/2006
2	3-Phosphoshikimate 1-Carboxyvinyltransferase (3 Phosphoshikimate 1 Carboxyvinyltransferase)IBA 08/2006 - 04/2003
2	Oxidoreductases (Dehydrogenase)IBA 01/2006 - 03/2004
1	MetalsIBA 01/2018
1	2- ((3- (1,3- benzodioxol- 5- yl)- 3- (((6- methoxy- 2- naphthyl)sulfonyl)amino)propanoyl)amino)- 3- (4- ((2,6- dimethylpiperidinyl)methyl)phenyl)- N- isopropyl- N- methylpropanamideIBA 01/2018
1	icatibantIBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 01/2016
1	Carrier Proteins (Binding Protein)IBA 01/2016
1	UridineIBA 12/2014
1	Fluorouracil (Carac)FDA LinkGeneric 12/2014
1	Annexin A5IBA 04/2014
1	Biological ProductsIBA 09/2013
1	LigandsIBA 09/2013
1	Purinergic P2X7 ReceptorsIBA 08/2013
1	VaccinesIBA 01/2012
1	Uridine PhosphorylaseIBA 05/2010
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 05/2010
1	Messenger RNA (mRNA)IBA 09/2009
1	Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)IBA 08/2009
1	purine phosphoribosyltransferaseIBA 08/2009
1	Cytidine Monophosphate (CMP)IBA 04/2009
1	Deoxycytidine Monophosphate (DCMP)IBA 04/2009
1	Proteins (Proteins, Gene)FDA Link 04/2008
1	Filgrastim (Neupogen)FDA Link 04/2008
1	Tyrosine (L-Tyrosine)FDA Link 01/2008
1	Phenylalanine (L-Phenylalanine)FDA Link 01/2008
1	Tryptophan (L-Tryptophan)FDA Link 01/2008
1	Ethionamide (Trecator-SC)FDA Link 02/2005
1	ThioamidesIBA 02/2005
1	pyridineIBA 02/2005
1	ProdrugsIBA 02/2005
1	Mutant Proteins (Protein, Mutant)IBA 03/2004
1	Isopropyl Thiogalactoside (IPTG)IBA 04/2003

Therapy/Procedure

5	Therapeutics 12/2014 - 02/2005
4	Drug Therapy (Chemotherapy) 12/2014 - 04/2008
1	Organ Transplantation 10/2005